Record-breaking COVID case: 72-year-old patient battled the virus for 613 days, acquiring over 50 mutations before succumbing to it

A Dutch man endured the longest case of COVID infection ever documented, battling the illness for a remarkable 613 days. Throughout this time, the virus mutated, giving rise to a perplexing and unprecedented variant that left medical experts puzzled.

According to research from the University of Amsterdam, the omicron variant was diagnosed in a 72-year-old patient in February 2022, as reported by Time.

According to researchers, this individual holds the record for the longest duration of viral infection.

Despite receiving the vaccine multiple times, the patient, who had pre-existing blood disease, experienced a failure in their immune system. This resulted in insufficient production of white blood cells and antibodies to effectively combat the COVID virus.

Despite the fact that the majority of individuals can recover from the coronavirus within a few weeks, all the medical interventions attempted by healthcare professionals failed to successfully treat the patient and eradicate the virus.

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Doctors discovered that his body had developed resistance to Sotrovimab—aa monoclonal antibody used in the early treatment of COVID-19—after obtaining over two dozen nose and throat swabs while searching for treatment.

They also discovered that the creation of an anti-spike antibody in the first month was negligible, indicating that the patient’s immune system was incapable of eliminating the virus.

The patient to die in the hospital in the fall of 2023 from a weakened immune system and an underlying blood condition.

However, experts discovered that the virus had mutated over 50 times while festering in his body, eventually producing an ultra-mutated form, according to the source.

Vergouwe stressed the significance of ongoing genomic surveillance of SARS-CoV-2 evolution in immunocompromised individuals who experience persistent infections. This is crucial due to the potential public health risk of introducing viral escape variants into the wider community.

According to a report by Time, scientists analyzing genomic data from wastewater have made a startling discovery. They have found evidence suggesting that humans may have been infected with highly mutated coronaviruses for over four years without even realizing it.

According to Vergouwe, this case has been added to the reports of patients who have tested positive for the same infection for more than a year. She mentioned that it is the longest case she has ever seen on record.

A British man holds the record for the longest duration of COVID-19 infection ever recorded. He battled with the virus for an astounding 505 days before tragically succumbing to it.

According to research, nearly a quarter (24.4%) of American adults who tested positive for COVID-19 have reported experiencing symptoms that lasted for three months or more.

Research conducted in the past has revealed that individuals who contracted COVID-19 prior to the emergence of the Omicron variant in 2021, were not vaccinated, or experienced reinfection, were more likely to experience long COVID. Moreover, the severity of long COVID was also found to be higher in these patient groups.

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